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High Amniotic
Fluid Levels : Polyhydramnios
High levels of amniotic fluid
can cause complications in pregnancy. The amniotic fluid is part of the
baby’s life support system. It protects your baby and aids in the
development of muscles, limbs, lungs and the digestive system. Amniotic
fluid is produced soon after the amniotic sac forms, about 12 days after
conception. It is first made up of water that is provided by the mother.
After about 20 weeks into the pregnancy, it is primarily made up of fetal
urine. As the baby grows, he or she will move and tumble in the womb with
the help of the amniotic fluid. In the second trimester the baby will
begin to breathe and swallow the amniotic fluid. Amniotic fluid levels
increase regularly until about 32-33 weeks gestation, and then they level
off. In some cases the amniotic fluid may measure too low or too high.
Normal fluid levels may vary, but are usually considered an AFI of 5-25
centimeters or a fluid level of about 800-1000 mL. If the measurement of
amniotic fluid is too low it is called oligohydramnios. If the measurement
of amniotic fluid is too high it is called polyhydramnios.
What is Polyhydramnios ?
Polyhydramnios is the condition of having too much amniotic fluid. Doctors
can measure the amount of fluid through a few different methods, most
commonly through amniotic fluid index (AFI) evaluation or deep pocket
measurements. If an AFI shows a fluid level of more than 25 centimeters
(or above the 95th percentile), a single deep pocket measurement of <8, or
a fluid level of 2000mL or more, then a diagnosis of polyhydramnios would
be made. About 1-2% of pregnant women have too much amniotic fluid. Most
of these cases are mild, with only slightly elevated levels.
What causes levels of amniotic fluid to be elevated ?
Congenital defects – The higher the fluid level, the increased chance of a
congenital defect. These birth defects hinder swallowing, which can
prohibit ingestion of the amniotic fluid, resulting in build up of fluid.
Other birth defects could also include intestinal tract blockage or
neurological abnormalities.
Rh Factor – As screening for the Rh factor has increased, this is no
longer a common cause of elevated fluid levels.
Maternal Diabetes – Experts have found some correlation between diabetes
and too much amniotic fluid.
Twin-to-twin transfusion syndrome – This is a complication that can affect
identical twin pregnancies. This syndrome is when one baby gets too much
blood flow and the other too little due to connections between blood
vessels in their shared placenta.
Unknown Reasons – According to the Center for Maternal Fetal Medicine,
about 65% of cases of polyhydramnios are due to unknown causes.
What are the risks of having too much amniotic fluid ?
Most cases of polyhydramnios are mild and result in few, if any,
complications. Those with higher levels of fluid could experience one or
more of the following risks:
* Premature rupture of the membranes (PROM)
* Placental abruption
* Preterm labor and delivery (approximately 26%)
* Growth restriction (IUGR) resulting in skeletal malformations
* Stillbirth occurs in about 4 in 1000 pregnancies that suffer from
polyhydramnios vs. about 2 in1000 pregnancies with normal fluid levels.
* Cesarean delivery
* Postpartum hemorrhage
What are the treatments for elevated amniotic fluid levels ?
Many cases of polyhydramnios are easily treated and do not result in
complications if the pregnancy is monitored closely. Monitoring would
include frequent sonograms measuring growth, biophysical profile and fetal
assessment. Other treatments could include:
* Medication that can reduce fluid production and are as much as 90%
effective. This treatment is not used after 32 weeks gestation because of
possible complications.
* Amnioreduction is a procedure that can be used to drain excess fluids.
This is done through amniocentesis, which may carry certain risks. There
is, however, the chance that fluid could build back up even after
draining.
* Delivery of the baby.
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